Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21102261 | 0.97 | ALDH1A1 (0.42) | ALDH1A1MAPK1PTPRCSLC6A3LMNA | |
| SCHEMBL21102406 | 0.97 | ALDH1A1 (0.42) | ALDH1A1MAPK1PTPRCSLC6A3LMNA | |
| SCHEMBL21102393 | 0.93 | ALDH1A1 (0.40) | ALDH1A1MAPK1SLC6A3LMNANPSR1 | |
| SCHEMBL21102400 | 0.84 | ALDH1A1 (0.39) | ALDH1A1MAPK1PTPRCLMNAMAPT | |
| SCHEMBL14178382 | 0.82 | PTGDR2 (0.35) | ALDH1A1MAPK1SLC6A3MEN1KMT2A | |
| SCHEMBL21102398 | 0.80 | PTPRC (0.39) | ALDH1A1MAPK1PTPRCLMNANPSR1 | |
| SCHEMBL21102403 | 0.79 | GPR84 (0.35) | ALDH1A1PTPRCMAPTMEN1NPC1 | |
| SCHEMBL16585739 | 0.79 | PTGDR2 (0.43) | ALDH1A1MAPK1PTPRCLMNANPSR1 | |
| SCHEMBL31497075 | 0.78 | PGR (0.44) | ALDH1A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21102262 | 0.78 | SMN1; SMN2 (0.39) | MAPK1PTPRCMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308129-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-10-01 | — | — | US | disclosed |
| WO-2019115577-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308129-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | DDC, CHRM5, AFF2 | ALDH1A1 1738/4885MAPK1 3334/4885PTPRC 4475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.