SCHEMBL21113046

SCHEMBL21113046

CC(C)(C)OC(=O)N1CCN(c2ccc3c(=O)c4ccc(N5CCCCC5)cc4oc3c2)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.49
▸ ALDH1A1 P00352 1/20 0.49
▸ LMNA P02545 1/20 0.49
▸ PDK2 Q15119 1/20 0.48
▸ GPR119 Q8TDV5 6/20 0.44
▸ CA12 O43570 1/20 0.44
▸ CA1 P00915 1/20 0.44
▸ CA2 P00918 1/20 0.44
▸ CA4 P22748 1/20 0.44
▸ CA5A P35218 1/20 0.44
▸ CA7 P43166 1/20 0.44
▸ CA5B Q9Y2D0 1/20 0.44
▸ NAMPT P43490 1/20 0.43
▸ TGFBR1 P36897 1/20 0.42
▸ SMN1; SMN2 Q16637 3/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ CSF1R P07333 2/20 0.42
▸ HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2394813 0.95 MAPT (0.53) MAPTALDH1A1LMNAPDK2GPR119
SCHEMBL19644239 0.84 PDK2 (0.45) MAPTALDH1A1LMNAPDK2GPR119
SCHEMBL29547579 0.84 PDK2 (0.45) MAPTALDH1A1LMNAPDK2GPR119
SCHEMBL3201431 0.82 CA12 (0.52) MAPTALDH1A1LMNAPDK2GPR119
SCHEMBL14304472 0.82 ALDH1A1 (0.55) MAPTALDH1A1LMNAGPR119CA12
SCHEMBL1937493 0.80 HSD17B10 (0.51) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL1937101 0.79 HSD17B10 (0.53) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL32677438 0.79 HSD17B10 (0.53) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL15066104 0.78 ALDH1A1 (0.52) MAPTALDH1A1LMNAPDK2GPR119
SCHEMBL24518077 0.78 ALDH1A1 (0.48) MAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230313277-A1 QUENCHER AND USE THEREOF SFC CO., LTD. (KR) 2023-10-05 — — US disclosed
US-20230313277-A1 QUENCHER AND USE THEREOF SFC CO., LTD. (KR) 2023-10-05 — — US disclosed
WO-2022124789-A1 QUENCHER AND USE THEREOF 에스에프씨 주식회사 2022-06-16 — — WO disclosed
US-10982262-B2 Quencher and use thereof SFC CO., LTD. (KR) 2021-04-20 — — US disclosed
US-20190194730-A1 QUENCHER AND USE THEREOF SFC CO., LTD. (KR) 2019-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194730-A1 QUENCHER AND USE THEREOF NQO1, SQOR, GPX4 MAPT 3102/4885ALDH1A1 1605/4885LMNA 1365/4885
US-10982262-B2 Quencher and use thereof NQO1, SQOR, GPX4 MAPT 3102/4885ALDH1A1 1605/4885LMNA 1365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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