Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21113046 | 0.95 | MAPT (0.49) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL14304472 | 0.86 | ALDH1A1 (0.55) | MAPTALDH1A1LMNAGPR119CA12 | |
| SCHEMBL3201431 | 0.86 | CA12 (0.52) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL19644239 | 0.83 | PDK2 (0.45) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL29547579 | 0.83 | PDK2 (0.45) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL15066104 | 0.82 | ALDH1A1 (0.52) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL28716306 | 0.80 | MAPT (0.46) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL29433670 | 0.80 | MAPT (0.46) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL24793535 | 0.80 | LMNA (0.50) | MAPTALDH1A1LMNAPDK2GPR119 | |
| SCHEMBL24794177 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1LMNAPDK2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212955-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | CANCER RESEARCH INITIATIVES FOUNDATION (MY) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212955-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | LTB4R, LTB4R2, NR1H3 | MAPT 4883/4885ALDH1A1 379/4885LMNA 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.