⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19963562 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL19951572 | 0.75 | TGFBR1 (0.44) | — | |
| SCHEMBL19951581 | 0.68 | NPSR1 (0.56) | — | |
| SCHEMBL19963651 | 0.67 | CYP2C9 (0.33) | — | |
| SCHEMBL23925357 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL19951565 | 0.66 | FOLH1 (0.50) | — | |
| SCHEMBL30374615 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL24334152 | 0.65 | TSHR (0.37) | — | |
| SCHEMBL15886981 | 0.64 | CTSK (0.44) | — | |
| SCHEMBL22702034 | 0.63 | ACE (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194250-A1 | PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2019-06-27 | — | — | US | disclosed |