Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | UTRN | P46939 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11934534 | 0.86 | GAA (0.51) | AKR1B1SLC27A1GRK6AGPAT2UTRN | |
| SCHEMBL6785675 | 0.83 | GAA (0.44) | AKR1B1SLC27A1ACLYNPC1RAB9A | |
| SCHEMBL30358398 | 0.83 | NPC1 (0.46) | AKR1B1ACLYNPC1RAB9AGFER | |
| SCHEMBL28876443 | 0.83 | NPC1 (0.46) | AKR1B1ACLYNPC1RAB9AGFER | |
| SCHEMBL30612620 | 0.83 | AKR1B1 (0.45) | AKR1B1SLC27A1NPC1RAB9AGRK6 | |
| SCHEMBL2792614 | 0.83 | AKR1B1 (0.45) | AKR1B1SLC27A1NPC1RAB9AGRK6 | |
| SCHEMBL9320795 | 0.83 | AKR1B1 (0.45) | AKR1B1SLC27A1NPC1RAB9AGRK6 | |
| SCHEMBL15707863 | 0.83 | AKR1B1 (0.45) | AKR1B1SLC27A1NPC1RAB9AGRK6 | |
| SCHEMBL5734937 | 0.80 | ACLY (0.45) | AKR1B1SLC27A1ACLYNPC1RAB9A | |
| SCHEMBL23176649 | 0.79 | KDM4E (0.53) | ACLYNPC1RAB9AGRK6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | B3GNT2, RPN2, RPN1 | AKR1B1 3678/4885SLC27A1 2848/4885ACLY 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.