Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PTGES | O14684 | 7/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21130354 | 0.93 | LMNA (0.56) | LMNAPTGESELANEPOLBKDM4E | |
| SCHEMBL21130273 | 0.87 | LMNA (0.65) | LMNAELANEPOLBKDM4EALDH1A1 | |
| SCHEMBL21130271 | 0.84 | LMNA (0.48) | LMNAPTGESPOLBKDM4EALDH1A1 | |
| SCHEMBL21130279 | 0.81 | LMNA (0.58) | LMNAELANEPOLBKDM4EALDH1A1 | |
| SCHEMBL2706715 | 0.81 | LMNA (0.56) | LMNAELANEPOLBKDM4EKMT2A | |
| SCHEMBL19749169 | 0.79 | LMNA (0.54) | LMNAELANEPOLBKDM4EALDH1A1 | |
| SCHEMBL21130276 | 0.79 | LMNA (0.56) | LMNAPTGESELANEPOLBKDM4E | |
| SCHEMBL10421505 | 0.79 | LMNA (1.00) | LMNAELANEPOLBKDM4EALDH1A1 | |
| SCHEMBL2493716 | 0.78 | L3MBTL1 (0.43) | LMNAPTGESPOLBKDM4EALDH1A1 | |
| SCHEMBL21130274 | 0.78 | LMNA (0.55) | LMNAELANEPOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | B3GNT2, RPN2, RPN1 | LMNA 1548/4885PTGES 436/4885ELANE 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.