Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 7/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.32 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21130281 | 0.84 | LMNA (0.64) | LMNAALDH1A1PTGESF2RL3KMT2A | |
| SCHEMBL21130354 | 0.78 | LMNA (0.56) | LMNAALDH1A1PTGESF2RL3KMT2A | |
| SCHEMBL21654403 | 0.77 | MEN1 (0.52) | LMNAALDH1A1F2RL3KMT2AMEN1 | |
| SCHEMBL2493716 | 0.73 | L3MBTL1 (0.43) | LMNAALDH1A1PTGESF2RL3KMT2A | |
| SCHEMBL21130273 | 0.72 | LMNA (0.65) | LMNAALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL6010846 | 0.70 | LMNA (0.38) | LMNAALDH1A1PTGESF2RL3KMT2A | |
| SCHEMBL7900050 | 0.70 | ALDH1A1 (0.46) | LMNAALDH1A1PTGESKMT2AMEN1 | |
| SCHEMBL12677385 | 0.69 | RAB9A (0.47) | LMNAALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL13515308 | 0.69 | NPC1 (0.48) | LMNAALDH1A1F2RL3KMT2AMEN1 | |
| SCHEMBL8221220 | 0.69 | F2RL3 (0.42) | F2RL3KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | B3GNT2, RPN2, RPN1 | LMNA 1548/4885ALDH1A1 3333/4885PTGES 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.