Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PGK1 | P00558 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.32 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21130358 | 0.94 | LMNA (0.49) | LMNAPGK1KDM4EPOLBNOTUM | |
| SCHEMBL21130356 | 0.84 | LMNA (0.41) | LMNAPGK1KDM4EPOLBGRM2 | |
| SCHEMBL19914260 | 0.82 | PGK1 (0.49) | LMNAPGK1KDM4EPOLBNOTUM | |
| SCHEMBL21130359 | 0.81 | LMNA (0.41) | LMNAPGK1KDM4EPOLBGRM2 | |
| SCHEMBL21130273 | 0.80 | LMNA (0.65) | LMNAKDM4EPOLBELANEFBP1 | |
| SCHEMBL21130276 | 0.78 | LMNA (0.56) | LMNAKDM4EPOLBNOTUMCNR2 | |
| SCHEMBL21130279 | 0.77 | LMNA (0.58) | LMNAKDM4EPOLBF2RL3ELANE | |
| SCHEMBL19914266 | 0.77 | PGK1 (0.49) | LMNAPGK1KDM4EPOLBNOTUM | |
| SCHEMBL19914272 | 0.76 | PGK1 (0.48) | PGK1NOTUMEGLN1SLC1A5FBP1 | |
| SCHEMBL21130281 | 0.75 | LMNA (0.64) | LMNAKDM4EPOLBF2RL3ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | B3GNT2, RPN2, RPN1 | LMNA 1548/4885PGK1 754/4885KDM4E 3731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.