Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14377661 | 0.89 | MEN1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL21133708 | 0.84 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL15307694 | 0.78 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL14377658 | 0.78 | RIPK1 (0.40) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL14377656 | 0.75 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL18093608 | 0.75 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL21133771 | 0.74 | ALDH1A1 (0.37) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL14377695 | 0.74 | SMN1; SMN2 (0.37) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL22007687 | 0.74 | NPC1 (0.36) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16835498 | 0.74 | POLB (0.31) | NPC1RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10906875-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-02-02 | — | — | US | disclosed |
| US-20200157049-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-05-21 | — | — | US | disclosed |
| US-10343996-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10906875-B2 | Quaternary heteroatom containing compounds | SDHA, NQO1, SDHB | NPC1 1902/4885RAB9A 904/4885MEN1 758/4885 |
| US-10343996-B2 | Quaternary heteroatom containing compounds | SDHA, NQO1, SDHB | NPC1 1902/4885RAB9A 904/4885MEN1 758/4885 |
| US-20200157049-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | SDHA, NQO1, SDHB | NPC1 1902/4885RAB9A 904/4885MEN1 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.