Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133955 | 0.83 | — | — | |
| SCHEMBL21848493 | 0.81 | KDM4E (0.34) | POLB | |
| SCHEMBL18290075 | 0.75 | POLB (0.48) | POLBNLRP3 | |
| SCHEMBL21133951 | 0.72 | — | — | |
| SCHEMBL24179610 | 0.72 | P2RX7 (0.33) | POLBNLRP3 | |
| SCHEMBL26800387 | 0.70 | POLB (0.38) | POLBNLRP3 | |
| SCHEMBL27255623 | 0.66 | ELANE (0.39) | POLBNLRP3 | |
| SCHEMBL21848497 | 0.64 | MIF (0.30) | — | |
| SCHEMBL21133957 | 0.64 | CYP1A2 (0.33) | POLBNLRP3 | |
| SCHEMBL24218912 | 0.63 | VCAM1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10347476-B2 | Tuned synthetic dendrimer calibrants for mass spectrometry | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10347476-B2 | Tuned synthetic dendrimer calibrants for mass spectrometry | SRMS, SRM, DNMT1 | POLB 1028/4885NLRP3 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.