Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CYB5R3 | P00387 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FER | P16591 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135597 | 0.85 | RET (0.42) | PARP1LMNATSHRMEN1KMT2A | |
| SCHEMBL21135350 | 0.76 | LMNA (0.42) | LMNATSHRMEN1KMT2APOLB | |
| SCHEMBL6557130 | 0.75 | TSHR (0.50) | LMNATSHRMEN1KMT2APOLB | |
| SCHEMBL19568178 | 0.75 | TSHR (0.50) | LMNATSHRMEN1KMT2APOLB | |
| SCHEMBL21135343 | 0.68 | L3MBTL1 (0.41) | LMNATSHRMEN1KMT2APOLB | |
| SCHEMBL21135378 | 0.67 | ALDH1A1 (0.36) | LMNATSHRKMT2AKDM4EHSD17B10 | |
| SCHEMBL22131494 | 0.64 | MEN1 (0.40) | PARP1LMNATSHRMEN1KMT2A | |
| SCHEMBL19854691 | 0.62 | PTPRC (0.46) | LMNATSHRMEN1KMT2AKDR | |
| SCHEMBL21135349 | 0.61 | L3MBTL1 (0.45) | LMNATSHRMEN1KMT2APOLB | |
| SCHEMBL9899341 | 0.61 | IDO1 (0.45) | LMNATSHRKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194464-A1 | MODIFIED DYE COMPOUNDS AND METHODS OF DYEING SUBSTRATES | THE H.D. LEE COMPANY, INC. | 2019-06-27 | — | — | US | disclosed |