Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22060236 | 0.79 | SLC15A1 (0.62) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL18822922 | 0.73 | CA2 (0.47) | KDM4E | |
| Phenylalanine Amide SCHEMBL353251 | 0.71 | SLC7A5 (0.73) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine Amide SCHEMBL244303 | 0.71 | SLC7A5 (0.73) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine Amide SCHEMBL11349868 | 0.71 | SLC7A5 (0.73) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine Amide SCHEMBL244302 | 0.71 | SLC7A5 (0.73) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine Amide SCHEMBL23002157 | 0.69 | SLC7A5 (0.70) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL918401 | 0.69 | SLC7A5 (0.71) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine Amide SCHEMBL7613303 | 0.69 | SLC7A5 (0.70) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine Amide SCHEMBL7613300 | 0.69 | SLC7A5 (0.70) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961273-B2 | N-carboxyanhydride-based-scale synthesis of elamipretide | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2021-03-30 | — | — | US | disclosed |
| US-20190202861-A1 | N-CARBOXYANHYDRIDE-BASED-SCALE SYNTHESIS OF ELAMIPRETIDE | STEALTH BIOTHERAPEUTICS INC. | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961273-B2 | N-carboxyanhydride-based-scale synthesis of elamipretide | MTPN, TUFM, PDF | SLC7A5 1906/4885PTGS1 2017/4885ALPI 1007/4885 |
| US-20190202861-A1 | N-CARBOXYANHYDRIDE-BASED-SCALE SYNTHESIS OF ELAMIPRETIDE | MTPN, TUFM, PDF | SLC7A5 1906/4885PTGS1 2017/4885ALPI 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.