Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 12/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 11/20 | 0.57 |
| ▸ | CCNB2 | O95067 | 10/20 | 0.57 |
| ▸ | CCNB3 | Q8WWL7 | 10/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 4/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.43 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18510350 | 0.89 | CDK1 (0.71) | CDK1CCNB1CCNB2CCNB3HTT | |
| SCHEMBL21539482 | 0.88 | CCNB2 (0.66) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL21943153 | 0.86 | CDK1 (0.61) | CDK1CCNB1CCNB2CCNB3HTT | |
| SCHEMBL21128138 | 0.80 | YTHDC1 (0.58) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL18520987 | 0.79 | HTT (0.58) | CDK1CCNB1CCNB2CCNB3HTT | |
| SCHEMBL18520056 | 0.79 | YTHDC1 (0.61) | CDK1CCNB1CCNB2CCNB3HTT | |
| SCHEMBL22326757 | 0.78 | HTT (0.62) | CDK1CCNB1CCNB2CCNB3HTT | |
| SCHEMBL18521194 | 0.76 | CCNB2 (0.82) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL22326729 | 0.76 | ADORA2A (0.66) | CDK1CCNB1CCNB2CCNB3HTT | |
| SCHEMBL16707340 | 0.74 | CDK1 (0.67) | CDK1CCNB1CCNB2CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066047-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-02-29 | — | — | US | disclosed |
| US-20210137962-A9 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-05-13 | — | — | US | disclosed |
| US-10980825-B2 | Cyclic dinucleotide | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-04-20 | — | — | US | disclosed |
| US-10759825-B2 | Cyclic di-nucleotide compounds as STING agonists | MERCK SHARP & DOHME CORP. (US) | 2020-09-01 | — | — | US | disclosed |
| US-20190192549-A1 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICALS CO (JP) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066047-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE | STING1, TLR9, CGAS | CDK1 4739/4885CCNB1 4816/4885CCNB2 4833/4885 |
| US-20210137962-A9 | CYCLIC DINUCLEOTIDE | STING1, CGAS, MAVS | CDK1 4501/4885CCNB1 4771/4885CCNB2 4744/4885 |
| US-10980825-B2 | Cyclic dinucleotide | STING1, CGAS, MAVS | CDK1 4501/4885CCNB1 4771/4885CCNB2 4744/4885 |
| US-20190192549-A1 | CYCLIC DINUCLEOTIDE | STING1, CGAS, MAVS | CDK1 4501/4885CCNB1 4771/4885CCNB2 4744/4885 |
| US-10759825-B2 | Cyclic di-nucleotide compounds as STING agonists | STING1, CGAS, IFNAR1 | CDK1 1642/4885CCNB1 2975/4885CCNB2 2974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.