Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.66 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.66 |
| ▸ | PI4KA | P42356 | 1/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 5/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326727 | 0.88 | ADORA2A (0.69) | ADORA2AADORA1TMIGD3HTTADORA2B | |
| SCHEMBL18520056 | 0.82 | YTHDC1 (0.61) | ADORA2AADORA1TMIGD3HTTCDK1 | |
| SCHEMBL22326757 | 0.82 | HTT (0.62) | ADORA2AADORA1TMIGD3HTTADORA2B | |
| SCHEMBL5051776 | 0.80 | ADORA2A (0.60) | ADORA2AADORA1TMIGD3HTTADORA2B | |
| SCHEMBL5839632 | 0.80 | CDK1 (0.71) | CDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL18548917 | 0.80 | YTHDC1 (0.62) | ADORA2AADORA1TMIGD3ADORA2BPI4KA | |
| SCHEMBL21275931 | 0.79 | ADORA2A (0.59) | ADORA2AADORA1TMIGD3HTTADORA2B | |
| SCHEMBL25737286 | 0.79 | CDK1 (0.55) | HTTCDK1 | |
| SCHEMBL21943153 | 0.79 | CDK1 (0.61) | ADORA2AADORA1TMIGD3HTTADORA2B | |
| SCHEMBL18520987 | 0.79 | HTT (0.58) | ADORA2AADORA1TMIGD3HTTADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738074-B2 | Cyclic di-nucleotide compounds as STING agonists | MERCK SHARP & DOHME CORP. (US) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738074-B2 | Cyclic di-nucleotide compounds as STING agonists | STING1, CGAS, IFNAR1 | ADORA2A 72/4885ADORA1 36/4885TMIGD3 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.