Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17896578 | 0.92 | SMN1; SMN2 (0.58) | PPARDPPARAPTGDR2SMN1; SMN2ALOX15 | |
| SCHEMBL12527817 | 0.88 | PPARD (0.49) | PPARDPPARAPTGDR2SMN1; SMN2RXRA | |
| SCHEMBL14258069 | 0.88 | ALDH1A1 (0.47) | PPARDPPARAPTGDR2SMN1; SMN2ALOX15 | |
| SCHEMBL18794845 | 0.88 | PTGDR2 (0.50) | PPARDPPARAPTGDR2SMN1; SMN2ALOX15 | |
| SCHEMBL18056097 | 0.85 | RXRA (0.50) | PPARDPPARAPTGDR2SMN1; SMN2RXRA | |
| SCHEMBL10931313 | 0.83 | KDM4E (0.49) | RXRARXRBRXRGKDM4ESOD1 | |
| SCHEMBL31645913 | 0.82 | KDM4E (0.68) | PPARAPTGDR2ALOX15KDM4ELMNA | |
| SCHEMBL585546 | 0.82 | KDM4E (0.68) | PPARAPTGDR2ALOX15KDM4ELMNA | |
| SCHEMBL18255647 | 0.82 | PPARD (0.45) | PPARDPPARAPTGDR2SMN1; SMN2RXRA | |
| SCHEMBL20974260 | 0.81 | PPARD (0.47) | PPARDPPARAPTGDR2SMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088066-B1 | 3,5-BIS (TRIFLUOROMETHYL) PHENOXY CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1985-04-03 | — | — | EP | claimed |
| US-4416687-A | 3,5-Bis (trifluoromethyl)phenoxy carboxylic acids and derivatives thereof | MONSANTO COMPANY (US) | 1983-11-22 | — | — | US | claimed |
| EP-0088066-A1 | 3,5-Bis (trifluoromethyl) phenoxy carboxylic acids and derivatives thereof | MONSANTO COMPANY (US) | 1983-09-07 | — | — | EP | claimed |
| EP-2388003-B1 | Colchicine derivatives | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2021-12-29 | — | — | EP | disclosed |
| EP-3207929-B1 | COLCHICINE DERIVATIVES FOR THE TREATMENT OF CANCER | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2021-05-26 | — | — | EP | disclosed |
| US-20200181067-A1 | FLUORINATED AMIDE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | TRILLIUM THERAPEUTICS INC. (CA) | 2020-06-11 | — | — | US | disclosed |
| US-20200181067-A1 | FLUORINATED AMIDE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | TRILLIUM THERAPEUTICS INC. (CA) | 2020-06-11 | — | — | US | disclosed |
| US-10604476-B2 | Fluorinated amide derivatives and their uses as therapeutic agents | TRILLIUM THERAPEUTICS INC. (CA) | 2020-03-31 | — | — | US | disclosed |
| US-20180334425-A1 | FLUORINATED AMIDE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | TRILLIUM THERAPEUTICS INC. (CA) | 2018-11-22 | — | — | US | disclosed |
| EP-3207929-A2 | COLCHICINE DERIVATIVES | California Pacific Medical Center (US) | 2017-08-23 | — | — | EP | disclosed |
| WO-2017070795-A1 | FLUORINATED AMIDE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | TRILLIUM THERAPEUTICS INC. (CA) | 2017-05-04 | — | — | WO | disclosed |
| WO-2002056885-A1 | CAMPTOTHECIN DERIVATIVES | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2002-07-25 | — | — | WO | disclosed |
| US-6350756-B1 | USEFUL FOR TREATING CANCER; (20S) ESTERS WITH AN OXYALKANOIC ACID; | CALIFORNIA PACIFIC MEDICAL CENTER | 2002-02-26 | — | — | US | disclosed |
| EP-0922028-A1 | INHIBITORS OF PHOSPHOLIPASE ENZYMES | GENETICS INSTITUTE, INC. (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998008818-A1 | INHIBITORS OF PHOSPHOLIPASE ENZYMES | GENETICS INSTITUTE, INC. (US) | 1998-03-05 | — | — | WO | disclosed |
| US-4672065-A | TOMATO LATE BLIGHT | CHEVRON RESEARCH COMPANY (US) | 1987-06-09 | — | — | US | disclosed |
| US-4535087-A | FOR TOMATO LATE BLIGHT | CHEVRON RESEARCH COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0088066-B1 | 3,5-BIS (TRIFLUOROMETHYL) PHENOXY CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4416687-A | 3,5-Bis (trifluoromethyl)phenoxy carboxylic acids and derivatives thereof | MONSANTO COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0088066-A1 | 3,5-Bis (trifluoromethyl) phenoxy carboxylic acids and derivatives thereof | MONSANTO COMPANY (US) | 1983-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180334425-A1 | FLUORINATED AMIDE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | GRIN2A, ACHE, BDNF | PPARD 293/4885PPARA 337/4885PTGDR2 200/4885 |
| US-10604476-B2 | Fluorinated amide derivatives and their uses as therapeutic agents | GRIN2A, ACHE, BDNF | PPARD 293/4885PPARA 337/4885PTGDR2 200/4885 |
| US-20200181067-A1 | FLUORINATED AMIDE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | GRIN2A, ACHE, BDNF | PPARD 293/4885PPARA 337/4885PTGDR2 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.