Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960601 | 0.85 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL21140743 | 0.84 | HSD17B10 (0.62) | SMN1; SMN2ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL5950098 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAALDH1A1F2RL3MBTL1 | |
| SCHEMBL5561958 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL31093984 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL26386086 | 0.76 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1F2RL3MBTL1 | |
| SCHEMBL25111096 | 0.75 | ALDH1A1 (0.53) | SMN1; SMN2LMNAALDH1A1F2RL3MBTL1 | |
| SCHEMBL19262175 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1F2RL3MBTL1 | |
| SCHEMBL2735680 | 0.73 | HSD17B10 (0.65) | SMN1; SMN2LMNAALDH1A1F2RL3MBTL1 | |
| SCHEMBL13391043 | 0.73 | HSD17B10 (0.67) | SMN1; SMN2LMNAALDH1A1F2RL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | LOXL2, LOXL1, LOXL3 | SMN1; SMN2 4478/4885LMNA 1626/4885ALDH1A1 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.