Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21140306 | 0.84 | SMN1; SMN2 (0.52) | HSD17B10TSHRSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL30977682 | 0.83 | HSD17B10 (0.67) | HSD17B10TSHRSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL19592439 | 0.83 | HSD17B10 (0.67) | HSD17B10TSHRSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL19960601 | 0.78 | ALDH1A1 (0.51) | HSD17B10TSHRSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11874540 | 0.77 | HSD17B10 (0.74) | HSD17B10TSHRCA1CA2CA7 | |
| SCHEMBL11876425 | 0.76 | HSD17B10 (0.72) | HSD17B10TSHRCA1CA2CA7 | |
| SCHEMBL11873185 | 0.75 | HSD17B10 (0.74) | HSD17B10TSHRCA1CA2CA7 | |
| SCHEMBL11861860 | 0.75 | HSD17B10 (0.74) | HSD17B10TSHRCA1CA2CA7 | |
| SCHEMBL11877345 | 0.75 | HSD17B10 (0.74) | HSD17B10TSHRCA1CA2CA7 | |
| SCHEMBL1491201 | 0.75 | HSD17B10 (0.69) | HSD17B10TSHRCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | LOXL2, LOXL1, LOXL3 | HSD17B10 984/4885TSHR 1154/4885CA1 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.