Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21143006 | 1.00 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1TRPA1CTSK | |
| SCHEMBL21143027 | 0.79 | TSHR (0.42) | TSHRSMN1; SMN2ALDH1A1CTSK | |
| SCHEMBL21166542 | 0.79 | TSHR (0.42) | TSHRSMN1; SMN2ALDH1A1CTSK | |
| SCHEMBL28025132 | 0.74 | TRPA1 (0.40) | ALDH1A1TRPA1 | |
| SCHEMBL6910847 | 0.74 | TSHR (0.54) | TSHRSMN1; SMN2ALDH1A1CTSKCA2 | |
| SCHEMBL13859355 | 0.72 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1CTSKCA2 | |
| SCHEMBL11185898 | 0.72 | TRPA1 (0.37) | TRPA1 | |
| SCHEMBL11185899 | 0.72 | TRPA1 (0.37) | TRPA1 | |
| SCHEMBL1188283 | 0.71 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1TRPA1CTSK | |
| SCHEMBL1188285 | 0.71 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1TRPA1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601786-B | Branched trialkylamine precursors, intermediates, products made therefrom and methods of making | 伊士曼化工公司 | 2024-03-12 | — | — | CN | disclosed |
| US-10961180-B2 | Branched trialkyl amine oxides | EASTMAN CHEMICAL COMPANY (US) | 2021-03-30 | — | — | US | disclosed |
| EP-3737662-A1 | BRANCHED TRIALKYLAMINE PRECURSORS, INTERMEDIATES, PRODUCTS MADE THEREFROM AND PROCESSES OF MANUFACTURE | Eastman Chemical Company (US) | 2020-11-18 | — | — | EP | disclosed |
| CN-111601786-A | Branched trialkylamine precursors, intermediates, products made therefrom, and methods of making | 伊士曼化工公司 | 2020-08-28 | — | — | CN | disclosed |
| US-10640452-B2 | Branched trialkyl quaternary ammonium compounds | EASTMAN CHEMICAL COMPANY (US) | 2020-05-05 | — | — | US | disclosed |
| US-20190218170-A1 | BRANCHED TRIALKYLAMINE PRECURSORS, INTERMEDIATES, PRODUCTS MADE THEREFROM AND PROCESSES OF MANUFACTURE | EASTMAN CHEMICAL COMPANY (US) | 2019-07-18 | — | — | US | disclosed |
| US-20190218169-A1 | BRANCHED TRIALKYL AMINE OXIDES | EASTMAN CHEMICAL COMPANY (US) | 2019-07-18 | — | — | US | disclosed |
| US-20190218171-A1 | BRANCHED TRIALKYL QUATERNARY AMMONIUM COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218169-A1 | BRANCHED TRIALKYL AMINE OXIDES | C5, OR10J3, ALKBH5 | TSHR 2779/4885SMN1; SMN2 1079/4885ALDH1A1 409/4885 |
| US-20190218171-A1 | BRANCHED TRIALKYL QUATERNARY AMMONIUM COMPOUNDS | ELOVL3, ELOVL5, ALK | TSHR 3683/4885SMN1; SMN2 4250/4885ALDH1A1 1343/4885 |
| US-10640452-B2 | Branched trialkyl quaternary ammonium compounds | BCKDK, PFKL, GLUL | TSHR 3735/4885SMN1; SMN2 3404/4885ALDH1A1 4533/4885 |
| US-20190218170-A1 | BRANCHED TRIALKYLAMINE PRECURSORS, INTERMEDIATES, PRODUCTS MADE THEREFROM AND PROCESSES OF MANUFACTURE | ACADM, ALK, FASN | TSHR 2579/4885SMN1; SMN2 3502/4885ALDH1A1 1105/4885 |
| US-10961180-B2 | Branched trialkyl amine oxides | C5, OR10J3, ALKBH5 | TSHR 2779/4885SMN1; SMN2 1079/4885ALDH1A1 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.