Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.54 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | ARG1 | P05089 | 1/20 | 0.46 |
| ▸ | ARG2 | P78540 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | BHMT | Q93088 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21165632 | 1.00 | NOS2 (0.54) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL21144523 | 0.90 | MAPT (0.52) | NOS2MAPTALDH1A1KDM4ETHRB | |
| SCHEMBL19469422 | 0.86 | NOS2 (0.54) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL19469425 | 0.86 | NOS2 (0.54) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL19469426 | 0.86 | BHMT (0.51) | NOS2NOS1NOS3MAPTALDH1A1 | |
| SCHEMBL18979844 | 0.83 | MAPT (0.45) | NOS2NOS1NOS3MAPTALDH1A1 | |
| SCHEMBL18979845 | 0.83 | MAPT (0.45) | NOS2NOS1NOS3MAPTALDH1A1 | |
| SCHEMBL10043024 | 0.82 | MAPT (0.47) | NOS2MAPTALDH1A1KDM4ETHRB | |
| SCHEMBL27075214 | 0.82 | MAPT (0.47) | NOS2MAPTALDH1A1KDM4ETHRB | |
| SCHEMBL4953347 | 0.82 | ICMT (0.49) | MAPTALDH1A1KDM4ETHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730829-B2 | Compound exhibiting anti-oxidative or anti-inflammatory activity | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2020-08-04 | — | — | US | disclosed |
| US-20190218178-A1 | NOVEL COMPOUND EXHIBITING ANTI-OXIDATIVE OR ANTI-INFLAMMATORY ACTIVITY | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730829-B2 | Compound exhibiting anti-oxidative or anti-inflammatory activity | MPO, LPO, GPX1 | NOS2 24/4885NOS1 17/4885NOS3 28/4885 |
| US-20190218178-A1 | NOVEL COMPOUND EXHIBITING ANTI-OXIDATIVE OR ANTI-INFLAMMATORY ACTIVITY | MPO, LPO, TYR | NOS2 22/4885NOS1 18/4885NOS3 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.