SCHEMBL21144458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20561889	0.91	GPR35 (0.57)	GPR35KDM4EMAPTTDP1RAB9A
	SCHEMBL8114876	0.81	GPR35 (0.54)	GPR35KDM4EMAPTTDP1KMO
	SCHEMBL3823231	0.80	MAPT (0.58)	GPR35KDM4EMAPTTDP1RAB9A
	SCHEMBL15016693	0.79	GPR35 (0.55)	GPR35KDM4EMAPTTDP1RAB9A
	SCHEMBL6588938	0.78	ALOX15 (0.55)	GPR35KDM4EMAPTALOX15TSHR
	SCHEMBL2775988	0.77	ALOX15 (0.58)	GPR35KDM4EMAPTALOX15PKM
	SCHEMBL11187280	0.77	ALDH1A1 (0.50)	GPR35KDM4EMAPTTDP1TSHR
	SCHEMBL6591021	0.77	MEN1 (0.54)	GPR35KDM4EMAPTTDP1ALOX15
	SCHEMBL6591013	0.77	MEN1 (0.54)	GPR35KDM4EMAPTTDP1ALOX15
	SCHEMBL2908229	0.75	GPR35 (0.55)	GPR35KDM4EKMOALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.