Cadaverine Tartrate

Cadaverine Tartrate

SCHEMBL21145233

CCCN.CCCN.O=C(O)C(O)C(O)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 1/20 0.42
CHRM3 known ✓ P20309 1/20 0.42
HTR2A known ✓ P28223 1/20 0.42
ADRA1A known ✓ P35348 1/20 0.42
HRH1 known ✓ P35367 1/20 0.42
SLC6A3 known ✓ Q01959 1/20 0.42
ADRB2 known ✓ P07550 1/20 0.36
ADRB1 known ✓ P08588 1/20 0.36
ADRA2A known ✓ P08913 1/20 0.36
ADRA2B known ✓ P18089 1/20 0.36
ADRA2C known ✓ P18825 1/20 0.36
SLC6A2 known ✓ P23975 1/20 0.36
ADRA1D known ✓ P25100 1/20 0.36
TSHR P16473 3/20 0.56
GABRR1 P24046 2/20 0.44
TDP1 Q9NUW8 2/20 0.42
DRD3 P35462 2/20 0.42
AKR1A1 P14550 1/20 0.42
HTR2C P28335 1/20 0.42
HDAC1 Q13547 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cadaverine Tartrate SCHEMBL7264837 1.00 TSHR (0.56) TSHRGABRR1TDP1DRD3CHRM1
Tartaric Acid SCHEMBL29438805 1.00 TSHR (0.56) TSHRGABRR1TDP1DRD3CHRM1
Cadaverine Tartrate SCHEMBL5874705 0.88 TSHR (0.62) TSHRGABRR1TDP1DRD3CHRM1
Tartaric Acid SCHEMBL30628132 0.88 TSHR (0.62) TSHRGABRR1TDP1DRD3CHRM1
Cadaverine Tartrate SCHEMBL5874700 0.88 TSHR (0.62) TSHRGABRR1TDP1DRD3CHRM1
Cadaverine Tartrate SCHEMBL11111704 0.87 TSHR (0.48) TSHRGPR84FFAR1MAPK1
Cadaverine Tartrate SCHEMBL2158124 0.85 TSHR (0.67) TSHRTDP1DRD3CHRM1AKR1A1
Cadaverine Tartrate SCHEMBL342524 0.85 TSHR (0.67) TSHRGABRR1TDP1DRD3KDM4E
Cadaverine Tartrate SCHEMBL786877 0.85 TSHR (0.67) TSHRGABRR1TDP1DRD3KDM4E
Decylamine SCHEMBL10879941 0.84 DNM1 (0.56) TSHRGPR84FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
EP-3518878-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION Henkel AG & Co. KGaA (DE) 2019-08-07 EP disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 CHRM1 2176/4885CHRM3 2150/4885HTR2A 267/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK CHRM1 1477/4885CHRM3 1874/4885HTR2A 873/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA CHRM1 1776/4885CHRM3 1740/4885HTR2A 526/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 CHRM1 1565/4885CHRM3 1661/4885HTR2A 666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.