Butyric Acid

Butyric Acid

SCHEMBL21145323

CCCC(=O)O.c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.58
HDAC3 O15379 2/20 0.56
HDAC1 Q13547 2/20 0.56
HDAC2 Q92769 2/20 0.56
HDAC8 Q9BY41 2/20 0.56
FFAR3 O14843 1/20 0.56
ALDH1A1 P00352 3/20 0.50
GLA P06280 1/20 0.50
TSHR P16473 1/20 0.50
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.46
HPGD P15428 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
KEAP1 Q14145 1/20 0.45
ALOX5 P09917 1/20 0.44
NR4A2 P43354 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPK1 P28482 1/20 0.42
ADRA1A P35348 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valeric Acid SCHEMBL21145154 0.88 AKR1B1 (0.52) TP53HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL27839710 0.88 TP53 (0.55) TP53HDAC3HDAC1HDAC2HDAC8
Hexanoate SCHEMBL21145144 0.86 AKR1B1 (0.61) ALDH1A1TSHRCES2CES1L3MBTL1
Dodecanoate SCHEMBL21145170 0.84 GPR84 (0.63) ALDH1A1TSHRCES2CES1NPSR1
Heptanoate SCHEMBL21145130 0.84 GPR84 (0.63) ALDH1A1TSHRCES2CES1NPSR1
Decanoic Acid SCHEMBL21145169 0.84 GPR84 (0.63) ALDH1A1TSHRCES2CES1NPSR1
Nonanoate SCHEMBL21145165 0.84 GPR84 (0.63) ALDH1A1TSHRCES2CES1NPSR1
Undecanoate SCHEMBL21145292 0.84 GPR84 (0.63) ALDH1A1TSHRCES2CES1NPSR1
Octanoic Acid SCHEMBL21145110 0.84 GPR84 (0.63) ALDH1A1TSHRCES2CES1NPSR1
Propionic Acid SCHEMBL21145220 0.84 ALDH1A1 (0.56) TP53FFAR3ALDH1A1GLATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 TP53 2105/4885HDAC3 778/4885HDAC1 121/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK TP53 2548/4885HDAC3 644/4885HDAC1 193/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA TP53 1209/4885HDAC3 803/4885HDAC1 116/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 TP53 1442/4885HDAC3 406/4885HDAC1 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.