SCHEMBL21148317

SCHEMBL21148317

C#CCCCCCCCCCCOc1cccc(N2CCN(CC3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]4OC(C)(C)O[C@@H]34)CC2)c1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 2/20 0.36
▸ DRD2 P14416 4/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ HTR1A P08908 3/20 0.33
▸ DRD4 P21917 1/20 0.33
▸ HTR2A P28223 1/20 0.33
▸ HRH1 P35367 1/20 0.33
▸ DRD3 P35462 1/20 0.33
▸ TMEM97 Q5BJF2 1/20 0.33
▸ SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21148318 1.00 KCNH2 (0.36) KCNH2DRD2ALDH1A1KMT2AMEN1
SCHEMBL21149379 0.78 KCNH2 (0.39) KCNH2DRD2HTR1ADRD4HTR2A
SCHEMBL21149371 0.78 DRD2 (0.50) DRD2ALDH1A1DRD4DRD3
SCHEMBL21149372 0.78 DRD2 (0.50) DRD2ALDH1A1DRD4DRD3
SCHEMBL21149325 0.78 ALDH1A1 (0.35) DRD2ALDH1A1KMT2AMEN1HTR1A
SCHEMBL21148820 0.72 DRD4 (0.41) DRD2ALDH1A1KMT2AMEN1HTR1A
SCHEMBL21148822 0.72 MAPT (0.42) DRD2ALDH1A1KMT2AMEN1DRD4
SCHEMBL21148637 0.71 ALDH1A1 (0.41) DRD2ALDH1A1DRD4DRD3
SCHEMBL21148636 0.62 CA2 (0.39) —
SCHEMBL24398779 0.59 ALDH1A1 (0.59) KCNH2ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11090364-B2 Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein SANOFI (FR) 2021-08-17 — — US disclosed
US-20190209656-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2019-07-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11090364-B2 Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein GPR119, SLC2A8, SLC2A4 KCNH2 4649/4885DRD2 4570/4885ALDH1A1 1514/4885
US-20190209656-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 KCNH2 4649/4885DRD2 4570/4885ALDH1A1 1514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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