Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 11/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21149371 | 1.00 | DRD2 (0.50) | DRD2DRD3HTR7OPRM1ALDH1A1 | |
| SCHEMBL21148637 | 0.87 | ALDH1A1 (0.41) | DRD2DRD3HTR7ALDH1A1DRD4 | |
| SCHEMBL24137899 | 0.87 | ALDH1A1 (0.41) | DRD2DRD3HTR7ALDH1A1DRD4 | |
| SCHEMBL21148820 | 0.81 | DRD4 (0.41) | DRD2DRD3ALDH1A1DRD4 | |
| SCHEMBL21148318 | 0.78 | KCNH2 (0.36) | DRD2DRD3ALDH1A1DRD4 | |
| SCHEMBL21148317 | 0.78 | KCNH2 (0.36) | DRD2DRD3ALDH1A1DRD4 | |
| SCHEMBL21148822 | 0.77 | MAPT (0.42) | DRD2ALDH1A1DRD4 | |
| SCHEMBL24145313 | 0.75 | DRD2 (0.42) | DRD2DRD3HTR7OPRM1ALDH1A1 | |
| SCHEMBL10190784 | 0.69 | CA2 (0.45) | ALDH1A1 | |
| SCHEMBL3453730 | 0.68 | DRD2 (1.00) | DRD2DRD3HTR7OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210401947-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-12-30 | — | — | US | disclosed |
| US-11090364-B2 | Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein | SANOFI (FR) | 2021-08-17 | — | — | US | disclosed |
| US-20190209656-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11090364-B2 | Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein | GPR119, SLC2A8, SLC2A4 | DRD2 4570/4885DRD3 4609/4885HTR7 3180/4885 |
| US-20190209656-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | DRD2 4570/4885DRD3 4609/4885HTR7 3180/4885 |
| US-20210401947-A1 | CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | DRD2 4570/4885DRD3 4609/4885HTR7 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.