SCHEMBL21150798

SCHEMBL21150798

CC(C)(C)OC(=O)N1CCC(N2CC(=O)N(c3ccccc3)C2=O)CC1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 6/20 0.57
USP30 Q70CQ3 2/20 0.47
TP53 P04637 2/20 0.47
KDM4E B2RXH2 2/20 0.47
PKM P14618 1/20 0.47
MAPT P10636 2/20 0.45
THRB P10828 2/20 0.45
STS P08842 1/20 0.44
FPR2 P25090 1/20 0.44
POLB P06746 1/20 0.44
NAMPT P43490 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21150756 0.79 GPR119 (0.37) GPR119TP53KDM4EMAPT
SCHEMBL21150805 0.78 YAP1 (0.46) KDM4EMAPT
SCHEMBL12511957 0.77 NAMPT (0.53) GPR119TP53KDM4EPKMMAPT
SCHEMBL4224097 0.76 GPR119 (0.58) GPR119TP53KDM4EPKMMAPT
SCHEMBL2959519 0.75 GPR119 (0.74) GPR119KDM4EMAPTTHRB
SCHEMBL21152121 0.75 ALDH1A1 (0.52) TP53KDM4EPKMMAPTPOLB
SCHEMBL3098616 0.74 TP53 (0.51) GPR119TP53KDM4EPKMNAMPT
SCHEMBL14334645 0.74 GPR119 (0.59) GPR119TP53KDM4EPKMMAPT
SCHEMBL21150819 0.74 TP53 (0.67) GPR119USP30TP53KDM4EPKM
SCHEMBL21150753 0.73 GRM4 (0.46) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 US disclosed
WO-2019136442-A1 CD16A BINDING AGENTS AND USES THEREOF KLEO PHARMACEUTICALS, INC. (US) 2019-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B GPR119 926/4885USP30 4473/4885TP53 138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.