Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21150818 | 0.80 | TSHR (0.44) | PTPRBPTPN11PKMKDM4E | |
| SCHEMBL21151307 | 0.70 | KDM1A (0.41) | — | |
| SCHEMBL21150835 | 0.69 | NR1H2 (0.39) | — | |
| SCHEMBL21152096 | 0.69 | OPRM1 (0.43) | POLBKDM4E | |
| SCHEMBL21150772 | 0.69 | ITGB3 (0.38) | POLBSLC6A9MAPT | |
| SCHEMBL21151877 | 0.67 | KMT2A (0.48) | SMN1; SMN2KDM4E | |
| SCHEMBL21150851 | 0.67 | GPR119 (0.39) | MAPT | |
| SCHEMBL24974652 | 0.62 | MT-CO2 (0.42) | POLBMAPTGAA | |
| SCHEMBL21150756 | 0.61 | GPR119 (0.37) | MAPTKDM4E | |
| SCHEMBL1146762 | 0.60 | FAAH (0.46) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |