Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL1130628 | 0.97 | HTR6 (0.32) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL2118673 | 0.83 | SIGMAR1 (0.31) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL812413 | 0.79 | HTR2A (0.33) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL29574347 | 0.79 | HTR2A (0.33) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6840560 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6843566 | 0.75 | — | — | |
| Fluoride Ion SCHEMBL1130437 | 0.75 | HTR2A (0.33) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6724657 | 0.75 | HTR6 (0.31) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6837857 | 0.74 | SIGMAR1 (0.35) | HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6698209 | 0.73 | BCHE (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597632-B1 | NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY | LG CHEMICAL LTD (KR) | 2013-03-27 | — | — | EP | claimed |
| EP-1597632-A4 | NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY | LG CHEMICAL LTD (KR) | 2009-08-26 | — | — | EP | claimed |
| US-20080281063-A9 | Ethylene polymers and copolymers with high optical opacity and methods of making the same | SUKHADIA ASHISH M | 2008-11-13 | — | — | US | claimed |
| US-7378206-B2 | Non-magnetic monocomponent positive toner composition having superior transfer efficiency | LG CHEM, LTD. (KR) | 2008-05-27 | — | — | US | claimed |
| US-7323524-B2 | Tandem tetramerisation-polymerisation of olefins | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2008-01-29 | — | — | US | claimed |
| US-7223822-B2 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-29 | — | — | US | claimed |
| US-20060128910-A1 | Tandem tetramerisation-polymerisation of olefins | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2006-06-15 | — | — | US | claimed |
| US-20060105260-A1 | Non-magnetic monocomponent positive toner composition having superior transfer efficiency | LG CHEM, LTD. (KR) | 2006-05-18 | — | — | US | claimed |
| EP-1597632-A1 | NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY | LG Chem, Ltd. (KR) | 2005-11-23 | — | — | EP | claimed |
| EP-1581343-A1 | TANDEM TETRAMERISATION-POLYMERISATION OF OLEFINS | Sasol Technology (PTY) Limited (ZA) | 2005-10-05 | — | — | EP | claimed |
| US-20050203261-A1 | Ethylene polymers and copolymers with high optical opacity and methods of making the same | CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. | 2005-09-15 | — | — | US | claimed |
| US-20040220359-A1 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-11-04 | — | — | US | claimed |
| WO-2004079456-A1 | NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY | LG CHEM, LTD. (KR) | 2004-09-16 | — | — | WO | claimed |
| WO-2004056480-A1 | TANDEM TETRAMERISATION-POLYMERISATION OF OLEFINS | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2004-07-08 | — | — | WO | claimed |
| US-6641925-B1 | Metallocene system catalyzed cycloolefin copolymer laminated to polyvinyl chloride; extrusion coated film as packaging | TICONA GMBH (DE) | 2003-11-04 | — | — | US | claimed |
| US-8957159-B2 | Multiple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8921291-B2 | Lubricants from mixed alpha-olefin feeds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-5422409-A | Stopping polymerization when molecular weight distribution Mw/Mn is less than 2 | HOECHST AKTIENGESELLSCHAFT | 1995-06-06 | — | — | US | disclosed |
| US-5331057-A | Cycloolefin block copolymers and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-19 | — | — | US | disclosed |
| US-5087677-A | Catalyst of a metallocene and an aluminoxane | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-11 | — | — | US | disclosed |