Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29574347 | 1.00 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Fluoride Ion SCHEMBL1130437 | 0.96 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL6916184 | 0.87 | GPR3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL2118673 | 0.83 | SIGMAR1 (0.31) | HTR2AHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6720593 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL2115117 | 0.79 | HTR6 (0.32) | HTR2AHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6732149 | 0.78 | HTR6 (0.31) | HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL7210554 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6724657 | 0.77 | HTR6 (0.31) | HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL7212371 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896525-B2 | Homogeneous polymerization process using evaporative cooling | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2018-02-20 | — | — | US | claimed |
| US-20160319054-A1 | Homogeneous Polymerization Process Using Evaporative Cooling | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-11-03 | — | — | US | claimed |
| US-20160115306-A1 | Polyolefin Adhesive Compositions and Methods of Preparing the Same | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-04-28 | — | — | US | claimed |
| US-9260635-B2 | Polyolefin adhesive compositions and methods for preparing the same | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-02-16 | — | — | US | claimed |
| EP-1597632-B1 | NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY | LG CHEMICAL LTD (KR) | 2013-03-27 | — | — | EP | claimed |
| JP-4664080-B2 | — | — | 2011-04-06 | — | — | JP | claimed |
| US-7741420-B2 | Polymer production at supercritical conditions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | claimed |
| EP-1597632-A4 | NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY | LG CHEMICAL LTD (KR) | 2009-08-26 | — | — | EP | claimed |
| US-7429634-B2 | Polymer production at supercritical conditions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-09-30 | — | — | US | claimed |
| US-7378206-B2 | Non-magnetic monocomponent positive toner composition having superior transfer efficiency | LG CHEM, LTD. (KR) | 2008-05-27 | — | — | US | claimed |
| EP-1539841-A1 | POLYMER PRODUCTION AT SUPERCRITICAL CONDITIONS | ExxonMobil Chemical Patents, Inc. a Corporation of the State of Delaware (US) | 2005-06-15 | — | — | EP | claimed |
| US-20040220359-A1 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-11-04 | — | — | US | claimed |
| WO-2004079456-A1 | NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY | LG CHEM, LTD. (KR) | 2004-09-16 | — | — | WO | claimed |
| US-20040138392-A1 | polyolefin adhesives; to produce reactor blends (also called intimate blends) of various polymers and other polymer compositions. | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-07-15 | — | — | US | claimed |
| US-20040127654-A1 | Polymer production at supercritical conditions | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-07-01 | — | — | US | claimed |
| WO-2004026921-A1 | POLYMER PRODUCTION AT SUPERCRITICAL CONDITIONS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-04-01 | — | — | WO | claimed |
| US-5708090-A | Process for the preparation of a polypropylene molding composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | claimed |
| US-5322902-A | Process for the preparation of a polypropylene molding composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-21 | — | — | US | claimed |
| US-5280074-A | Process for the preparation of a polypropylene molding composition | HOECHST AG (DE) | 1994-01-18 | — | — | US | claimed |
| EP-0384263-B1 | PROCESS FOR PREPARING A STATISTICAL PROPYLENE COPOLYMER | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | claimed |