Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6724657

C=C[SiH](C=C)[Hf+](C1C=Cc2ccccc21)C1C=Cc2ccccc21.C=C[SiH](C=C)[Hf+](C1C=Cc2ccccc21)C1C=Cc2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6720593 0.84
Hydrochloric Acid SCHEMBL6731804 0.80 HTR6 (0.32) HTR6HTR2A
Hydrochloric Acid SCHEMBL812413 0.77 HTR2A (0.33) HTR6HTR2A
Hydrochloric Acid SCHEMBL29574347 0.77 HTR2A (0.33) HTR6HTR2A
Hydrochloric Acid SCHEMBL6732149 0.77 HTR6 (0.31) HTR6HTR2A
Hydrochloric Acid SCHEMBL2115117 0.75 HTR6 (0.32) HTR6HTR2A
Fluoride Ion SCHEMBL1130437 0.74 HTR2A (0.33) HTR6HTR2A
Hydrochloric Acid SCHEMBL2118673 0.72 SIGMAR1 (0.31) HTR6HTR2A
Fluoride Ion SCHEMBL1130628 0.71 HTR6 (0.32) HTR6HTR2A
Hydrochloric Acid SCHEMBL7951349 0.71 HTR2A (0.36) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6746981-B2 OLEFIN POLYMERIZATION CATALYSTS WITH PRODUCTIVITY WHEN FRESH OF >/= 18,000 GRAMS OF POLYETHYLENE PER GRAM OF CATALYST IN ONE HOUR, AND A SPECIFIC SURFACE AREA OF </= 20 M2/G ALBEMARLE CORPORATION 2004-06-08 US disclosed
US-6730758-B2 ADDITION POLYMERIZATION OF ALPHA-OLEFIN HYDROCARBON IN PRESENCE OF SELF-SUPPORTED VINYLOLEFIN-PREPOLYMERIZED CATALYST ALBEMARLE CORPORATION 2004-05-04 US disclosed
EP-1037931-B1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORP (US) 2004-02-04 EP disclosed
US-6677265-B1 THE METALLOCENE USED AS THE FEED HAVING IN THE MOLECULE AT LEAST ONE POLYMERIZABLE OLEFINIC SUBSTITUENT ALBEMARLE CORPORATION 2004-01-13 US disclosed
US-20030191254-A1 PARTICULATE GROUP 4 METALLOCENE-ALUMINOXANE CATALYST COMPOSITIONS DEVOID OF PREFORMED SUPPORT, AND THEIR PREPARATION AND THEIR USE ALBEMARLE CORPORATION 2003-10-09 US disclosed
US-20030105253-A1 Particulate group 4 metallocene-aluminoxane catalyst compositions devoid of preformed support, and their preparation and their use ALBEMARLE CORPORATION 2003-06-05 US disclosed
US-6551955-B1 Olefin polymerization catalysts; efficiency ALBEMARLE CORPORATION 2003-04-22 US disclosed
US-6521728-B1 Particulate group 4 metallocene-aluminoxane catalyst compositions devoid of preformed support, and their preparation and their use ALBEMARLE CORPORATION 2003-02-18 US disclosed
WO-2001098381-A2 POLYMERIZATION PROCESS USING SELF-SUPPORTED CATALYSTS ALBEMARLE CORPORATION (US) 2001-12-27 WO disclosed
WO-2001098380-A2 PARTICULATE GROUP 4 METALLOCENE-ALUMINOXANE CATALYST COMPOSITIONS DEVOID OF PREFORMED SUPPORT, AND THEIR PREPARATION AND THEIR USE ALBEMARLE CORPORATION (US) 2001-12-27 WO disclosed
WO-2001098374-A2 PROCESS OF PRODUCING SELF-SUPPORTED CATALYSTS ALBEMARLE CORPORATION (US) 2001-12-27 WO disclosed
US-6294496-B1 VERY HIGH PRODUCTIVITIES; PREPOLYMERIZING VINYLOLEFIN WITH A GROUP 4 METALLOCENE-ALUMINOXANE SOLUTION ALBEMARLE CORPORATION 2001-09-25 US disclosed
EP-1037931-A1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORPORATION (US) 2000-09-27 EP disclosed
WO-1999029738-A1 CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY ALBEMARLE CORPORATION (US) 1999-06-17 WO disclosed