SCHEMBL21152102

SCHEMBL21152102

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)-c3ccccc3C43c4ccccc4Oc4c(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)cccc43)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.35
MAPT P10636 4/20 0.35
KMT2A Q03164 4/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 3/20 0.35
KDM4E B2RXH2 3/20 0.34
LMNA P02545 3/20 0.34
GLA P06280 1/20 0.34
ADORA3 P0DMS8 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
ADORA1 P30542 1/20 0.32
OPRK1 P41145 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24647755 0.97 MEN1 (0.33) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL21151609 0.93 MEN1 (0.35) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL19299149 0.93 TSHR (0.35) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL21651346 0.93 TSHR (0.35) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL20619107 0.93 TSHR (0.36) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL23814526 0.92 MEN1 (0.33) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL24648459 0.92 MEN1 (0.33) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL23814904 0.92 PDK2 (0.34) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL20619082 0.92 ADORA3 (0.33) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL22671971 0.92 PDK2 (0.34) MEN1MAPTKMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210288260-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2021-09-16 US disclosed
US-20210217967-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-07-15 US disclosed
WO-2020022768-A1 ORGANIC LIGHT EMITTING DIODE 주식회사 엘지화학 2020-01-30 WO disclosed
WO-2020022771-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2020-01-30 WO disclosed
US-20190214571-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214571-A1 ORGANIC LIGHT EMITTING DEVICE PPOX, ERO1A, HMOX2 MEN1 2280/4885MAPT 484/4885KMT2A 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.