SCHEMBL19299149

SCHEMBL19299149

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc5c4Oc4ccccc4C54c5ccccc5-c5ccccc54)n3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
ALOX15 P16050 2/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA2B P29275 1/20 0.35
ADORA1 P30542 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
MAPT P10636 4/20 0.32
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
ALDH1A1 P00352 3/20 0.32
HPGD P15428 3/20 0.32
KDM4E B2RXH2 3/20 0.31
LMNA P02545 3/20 0.31
MAPK1 P28482 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TP53 P04637 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21651346 1.00 TSHR (0.35) TSHRALOX15ADORA3ADORA2AADORA2B
SCHEMBL20619107 0.97 TSHR (0.36) TSHRALOX15ADORA3ADORA2AADORA2B
SCHEMBL22671971 0.96 PDK2 (0.34) TSHRALOX15ADORA3ADORA2AADORA2B
SCHEMBL23814904 0.96 PDK2 (0.34) TSHRALOX15ADORA3ADORA2AADORA2B
SCHEMBL20622683 0.95 TSHR (0.33) TSHRALOX15ADORA3ADORA2AADORA2B
SCHEMBL20622670 0.95 TSHR (0.33) TSHRALOX15ADORA3ADORA2AADORA2B
SCHEMBL20619327 0.95 GPR55 (0.34) TSHRALOX15ADORA3ADORA2AADORA2B
SCHEMBL20619317 0.95 GPR55 (0.34) TSHRALOX15ADORA3ADORA2AADORA2B
SCHEMBL19298359 0.95 GPR55 (0.34) TSHRALOX15ADORA3ADORA2AADORA2B
SCHEMBL20619082 0.94 ADORA3 (0.33) TSHRALOX15ADORA3ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11152576-B2 Organic light emitting device LG CHEM, LTD. (KR) 2021-10-19 US disclosed
US-20210288264-A1 Heterocyclic Compound And Organic Light Emitting Element Comprising Same LG CHEM, LTD. (KR) 2021-09-16 US disclosed
US-20210288260-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2021-09-16 US disclosed
US-11094889-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. 2021-08-17 US disclosed
US-20210217967-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-07-15 US disclosed
US-20210143344-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2021-05-13 US disclosed
US-20210020842-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-21 US disclosed
US-20210013422-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed
EP-3595025-B1 ORGANIC LIGHT EMITTING ELEMENT LG CHEMICAL LTD (KR) 2020-12-30 EP disclosed
US-20200388768-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2020-12-10 US disclosed
US-20200365814-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2020-11-19 US disclosed
US-20200035930-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-01-30 US disclosed
WO-2020022811-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2020-01-30 WO disclosed
WO-2020022768-A1 ORGANIC LIGHT EMITTING DIODE 주식회사 엘지화학 2020-01-30 WO disclosed
WO-2020022771-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2020-01-30 WO disclosed
WO-2019004782-A1 ORGANIC LIGHT EMITTING ELEMENT 주식회사 엘지화학 2019-01-03 WO disclosed
WO-2019004787-A1 ORGANIC LIGHT EMITTING ELEMENT 주식회사 엘지화학 2019-01-03 WO disclosed
WO-2017146466-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2017-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210288264-A1 Heterocyclic Compound And Organic Light Emitting Element Comprising Same CRY1, CRY2, PER2 TSHR 4112/4885ALOX15 652/4885ADORA3 3245/4885
US-11094889-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 TSHR 4112/4885ALOX15 652/4885ADORA3 3245/4885
US-20210020842-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, OR51E2, LOXL1 TSHR 2461/4885ALOX15 373/4885ADORA3 4367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.