SCHEMBL21152424

SCHEMBL21152424

Cc1cccc(B2OC(C)(C)C(C)(C)O2)c1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ LIPG Q9Y5X9 7/20 0.50
▸ LPL P06858 6/20 0.50
▸ ANPEP P15144 1/20 0.35
▸ LAP3 P28838 1/20 0.35
▸ FABP4 P15090 1/20 0.35
▸ BRD4 O60885 2/20 0.34
▸ TDO2 P48775 1/20 0.34
▸ JAK2 O60674 3/20 0.33
▸ BTK Q06187 3/20 0.33
▸ F11 P03951 1/20 0.33
▸ MAOA P21397 1/20 0.33
▸ MAOB P27338 1/20 0.33
▸ BRD2 P25440 1/20 0.33
▸ P4HB P07237 1/20 0.32
▸ RET P07949 1/20 0.32
▸ RPA1 P27694 1/20 0.32
▸ MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3958885 0.85 LIPG (0.49) LIPGLPLANPEPLAP3BRD4
SCHEMBL18462204 0.84 LIPG (0.58) LIPGLPLANPEPLAP3BRD4
SCHEMBL18090634 0.83 LPL (0.39) LIPGLPLANPEPLAP3JAK2
SCHEMBL18462118 0.83 LIPG (0.50) LIPGLPLANPEPLAP3P4HB
SCHEMBL21612973 0.80 LIPG (0.50) LIPGLPLANPEPLAP3BRD4
SCHEMBL6686927 0.80 LPL (0.47) LIPGLPLANPEPLAP3JAK2
SCHEMBL22319341 0.77 LIPG (0.44) LIPGLPL
SCHEMBL14878282 0.77 JAK2 (0.41) LIPGLPLJAK2BTK
SCHEMBL29829631 0.77 LIPG (0.50) LIPGLPLANPEPLAP3JAK2
SCHEMBL18727772 0.77 LIPG (0.50) LIPGLPLANPEPLAP3JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190214571-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-07-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214571-A1 ORGANIC LIGHT EMITTING DEVICE PPOX, ERO1A, HMOX2 LIPG 77/4885LPL 144/4885ANPEP 3244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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