Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.52 |
| ▸ | TP53 | P04637 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.49 |
| ▸ | USP2 | O75604 | 8/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117350 | 0.77 | CYP3A4 (0.54) | CYP3A4TP53ALDH1A1CYP2D6HPGD | |
| SCHEMBL10626283 | 0.77 | ALDH1A1 (0.64) | CYP3A4TP53ALDH1A1CYP2D6HPGD | |
| SCHEMBL22259649 | 0.76 | HPGD (0.53) | CYP3A4ALDH1A1HPGDTDP1CYP1A2 | |
| SCHEMBL1004649 | 0.74 | ALDH1A1 (0.73) | CYP3A4TP53ALDH1A1CYP2D6HPGD | |
| SCHEMBL2118444 | 0.74 | ALDH1A1 (0.49) | CYP3A4TP53ALDH1A1CYP2D6HPGD | |
| SCHEMBL3630523 | 0.73 | ALDH1A1 (0.59) | ALDH1A1HPGDTDP1CYP1A2CYP2C19 | |
| SCHEMBL2117285 | 0.71 | LMNA (0.57) | ALDH1A1CYP2D6HPGDKDM4EMEN1 | |
| SCHEMBL22575128 | 0.71 | CSNK2A1 (0.52) | CYP3A4TP53ALDH1A1CYP2D6HPGD | |
| SCHEMBL375967 | 0.71 | NPC1 (0.58) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL18924446 | 0.71 | HDAC1 (0.53) | CYP3A4TP53ALDH1A1CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158787-B2 | Process for producing trichloropyrimidine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20100160630-A1 | PROCESS FOR PRODUCING TRICHLOROPYRIMIDINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2128141-A1 | PROCESS FOR PRODUCING TRICHLOROPYRIMIDINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160630-A1 | PROCESS FOR PRODUCING TRICHLOROPYRIMIDINE COMPOUND | DPYD, TYMP, TST | CYP3A4 1172/4885TP53 161/4885ALDH1A1 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.