Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553905 | 0.90 | CYP11B2 (0.51) | HDAC1HDAC6SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL30731158 | 0.90 | CYP11B2 (0.51) | HDAC1HDAC6SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL353139 | 0.87 | KDM4E (0.60) | SMN1; SMN2HPGDALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10626283 | 0.87 | ALDH1A1 (0.64) | SMN1; SMN2HPGDALDH1A1KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL5796679 | 0.85 | KDM4E (0.58) | SMN1; SMN2HPGDALDH1A1KDM4ECYP1A2 | |
| SCHEMBL28391899 | 0.80 | MKNK1 (0.46) | SMN1; SMN2KDM4EHSD17B10KMT2AMAPT | |
| SCHEMBL30731092 | 0.80 | CHEK2 (0.72) | ATRMAPK1 | |
| SCHEMBL22554299 | 0.80 | CHEK2 (0.72) | ATRMAPK1 | |
| SCHEMBL1004649 | 0.80 | ALDH1A1 (0.73) | SMN1; SMN2HPGDALDH1A1KDM4ECYP1A2 | |
| SCHEMBL19076162 | 0.79 | KDM1A (0.59) | HDAC1HDAC6SMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150423-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| US-20180022738-A1 | 3-SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022738-A1 | 3-SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES | FASN, FADS1, ACOX3 | HDAC1 1503/4885HDAC6 4002/4885SMN1; SMN2 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.