Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20016488 | 0.83 | OPRK1 (0.33) | ITGB3ITGA2BOPRK1 | |
| SCHEMBL19062769 | 0.83 | OPRK1 (0.33) | ITGB3ITGA2BOPRK1 | |
| SCHEMBL24239548 | 0.83 | OPRK1 (0.33) | ITGB3ITGA2BOPRK1 | |
| SCHEMBL19700526 | 0.82 | MMP3 (0.38) | ITGB3ITGA2BOPRK1 | |
| SCHEMBL21902132 | 0.81 | OPRK1 (0.31) | ITGB3ITGA2BOPRK1 | |
| SCHEMBL24220950 | 0.77 | NMT2 (0.32) | ITGB3ITGA2B | |
| SCHEMBL18929779 | 0.76 | OPRK1 (0.30) | OPRK1 | |
| SCHEMBL16248631 | 0.75 | KDM4E (0.35) | ITGB3ITGA2BNPSR1 | |
| SCHEMBL25132732 | 0.75 | KDM4E (0.35) | ITGB3ITGA2BNPSR1 | |
| SCHEMBL17662433 | 0.75 | KDM4E (0.35) | ITGB3ITGA2BNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10751419-B2 | Method for synthesis of reactive conjugate clusters | IONIS PHARMACEUTICALS, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190209694-A1 | METHOD FOR SYNTHESIS OF REACTIVE CONJUGATE CLUSTERS | IONIS PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10751419-B2 | Method for synthesis of reactive conjugate clusters | ACOT7, COASY, LCAT | ITGB3 1933/4885ITGA2B 2143/4885OPRK1 4627/4885 |
| US-20190209694-A1 | METHOD FOR SYNTHESIS OF REACTIVE CONJUGATE CLUSTERS | ACOT7, COASY, LCAT | ITGB3 1933/4885ITGA2B 2143/4885OPRK1 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.