Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21157814 | 1.00 | NUDT1 (0.40) | NUDT1METAP2MAOBALDH1A1HPGD | |
| SCHEMBL21157905 | 0.85 | NUDT1 (0.44) | NUDT1METAP2MAOBALDH1A1HPGD | |
| SCHEMBL21157067 | 0.80 | NUDT1 (0.43) | NUDT1METAP2MAOBALDH1A1HPGD | |
| SCHEMBL21156614 | 0.80 | NUDT1 (0.43) | NUDT1METAP2MAOBALDH1A1HPGD | |
| SCHEMBL21157073 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPTPRKDCNPC1RAB9A | |
| SCHEMBL21157808 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPTPRKDCNPC1RAB9A | |
| SCHEMBL21157813 | 0.80 | PRKDC (0.45) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL21157074 | 0.80 | PRKDC (0.45) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL430107 | 0.78 | SMN1; SMN2 (0.40) | NUDT1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL21157897 | 0.77 | METAP2 (0.36) | NUDT1METAP2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190214577-A1 | THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190214577-A1 | THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE | TEAD2, TEAD3, TEAD1 | NUDT1 1200/4885METAP2 4724/4885MAOB 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.