Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18089666 | 0.82 | SMN1; SMN2 (0.40) | CYP2C9KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19886702 | 0.73 | POLB (0.42) | KMT2ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL18089740 | 0.70 | ALDH1A1 (0.34) | KDM4EPOLBLMNA | |
| SCHEMBL18089423 | 0.70 | ALDH1A1 (0.34) | KDM4EPOLBLMNA | |
| SCHEMBL21497101 | 0.68 | CYP2C9 (0.34) | CYP2C9KDM4EALOX15 | |
| SCHEMBL18089741 | 0.67 | LMNA (0.33) | KDM4EPOLBLMNA | |
| SCHEMBL18089660 | 0.66 | TP53 (0.36) | PKMALOX15 | |
| SCHEMBL18089736 | 0.65 | CYP2C9 (0.33) | CYP2C9KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL15868268 | 0.64 | SIGMAR1 (0.40) | KMT2ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL14751665 | 0.63 | SIGMAR1 (0.39) | KMT2ARAB9ASMN1; SMN2KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190211037-A1 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT | REMPEX PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190211037-A1 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT | BTD, BCL6B, BPGM | CYP2C19 2058/4885CYP2C9 2757/4885KMT2A 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.