SCHEMBL21158702

SCHEMBL21158702

c1ccc(C(c2ccc3c(c2)Oc2ccc(C(c4ccccc4)c4cc5ccccc5c5ccccc45)cc2O3)c2cc3ccccc3c3ccccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
NR3C2 P08235 1/20 0.33
AR P10275 1/20 0.33
TRPM4 Q8TD43 1/20 0.33
AHR P35869 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HIF1A Q16665 1/20 0.32
CYP1B1 Q16678 1/20 0.32
HSD17B10 Q99714 1/20 0.32
EDNRA P25101 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24851086 0.85
SCHEMBL24849086 0.76
SCHEMBL31409231 0.74 HPRT1 (0.39) TRPM4ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL10296824 0.74 TRPM4 (0.47) TRPM4ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL13520751 0.71 NQO1 (0.42) PGRAHRALDH1A1HSD17B10
SCHEMBL13520880 0.68 ALOX5 (0.47)
SCHEMBL14124778 0.67 ADORA2A (0.51) TRPM4ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL6527095 0.66 ALDH1A1 (0.40) AHRALDH1A1HSD17B10CYP1A2CYP2C19
SCHEMBL22855298 0.65 MGAM (0.39) ALDH1A1HSD17B10
SCHEMBL25395389 0.64 TRPM4 (0.37) TRPM4ALDH1A1HIF1ACYP1B1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11081659-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-08-03 US disclosed
US-20190214584-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214584-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, L1CAM, MCM2 NR3C1 4137/4885PGR 1039/4885NR3C2 2946/4885
US-11081659-B2 Organic electroluminescent materials and devices SOD1, L1CAM, MCM2 NR3C1 4137/4885PGR 1039/4885NR3C2 2946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.