SCHEMBL21158724

SCHEMBL21158724

Cc1cccc(-c2nc3ccccc3c3ccccc23)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.54
NR1I3 Q14994 1/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
ALDH1A1 P00352 4/20 0.51
TSHR P16473 2/20 0.51
MAPK1 P28482 1/20 0.51
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
GPR3 P46089 1/20 0.48
MAPT P10636 3/20 0.48
ABCB1 P08183 1/20 0.48
ABCG2 Q9UNQ0 1/20 0.48
LMNA P02545 1/20 0.47
TP53 P04637 2/20 0.47
PDE10A Q9Y233 1/20 0.46
MEN1 O00255 2/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24363687 0.86 GPR3 (0.52) KMT2ANR1I3NPC1RAB9AALDH1A1
SCHEMBL19449135 0.85 NR1I3 (0.52) KMT2ANR1I3NPC1RAB9AALDH1A1
SCHEMBL16202757 0.83 L3MBTL1 (0.63) KMT2ANR1I3NPC1RAB9AALDH1A1
SCHEMBL12136806 0.83 NR1I3 (0.62) KMT2ANR1I3NPC1RAB9AALDH1A1
SCHEMBL18503935 0.82 NR1I3 (0.50) KMT2ANR1I3NPC1RAB9AALDH1A1
SCHEMBL15860237 0.82 ALDH1A1 (0.69) KMT2ANR1I3NPC1RAB9AALDH1A1
SCHEMBL28159697 0.82 KMT2A (0.50) KMT2ANR1I3NPC1RAB9AALDH1A1
SCHEMBL18503937 0.82 KMT2A (0.50) KMT2ANR1I3NPC1RAB9AALDH1A1
SCHEMBL729919 0.81 NUDT1 (0.61) KMT2AALDH1A1TSHRKDM4EL3MBTL1
SCHEMBL30537037 0.81 NUDT1 (0.61) KMT2AALDH1A1TSHRKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3757100-B1 TRIAZINE COMPOUNDS SUBSTITUTED WITH BULKY GROUPS NOVALED GMBH (DE) 2022-12-28 EP disclosed
US-11530201-B2 Triazine compounds substituted with bulky groups NOVALED GMBH (DE) 2022-12-20 US disclosed
EP-3757100-A1 TRIAZINE COMPOUNDS SUBSTITUTED WITH BULKY GROUPS Novaled GmbH (DE) 2020-12-30 EP disclosed
US-20200361916-A1 Triazine Compounds substituted with Bulky Groups SAMSUNG SDI CO. LTD. (KR) 2020-11-19 US disclosed
EP-3502106-B1 TRIAZINE COMPOUNDS SUBSTITUTED WITH BULKY GROUPS NOVALED GMBH (DE) 2020-09-02 EP disclosed
EP-3503240-A1 ORGANIC SEMICONDUCTOR LAYER Novaled GmbH (DE) 2019-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530201-B2 Triazine compounds substituted with bulky groups POU5F1, POU2F1, IKZF2 KMT2A 465/4885NR1I3 2291/4885NPC1 3519/4885
US-20200361916-A1 Triazine Compounds substituted with Bulky Groups POU5F1, POU2F1, IKZF2 KMT2A 465/4885NR1I3 2291/4885NPC1 3519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.