Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20749368 | 0.77 | CYP2A6 (0.61) | KIF11MMP3ALDH1A1CYP2A6PTGS2 | |
| SCHEMBL13006754 | 0.67 | MMP3 (0.52) | LOXL2KIF11MMP3ALDH1A1CYP2A6 | |
| Methylhydrazine SCHEMBL3435836 | 0.65 | MMP3 (0.54) | LOXL2KIF11MMP3ALDH1A1CYP2A6 | |
| SCHEMBL13063633 | 0.65 | MMP3 (0.74) | LOXL2KIF11MMP3ALDH1A1CYP2A6 | |
| SCHEMBL26246 | 0.65 | MMP3 (0.74) | LOXL2KIF11MMP3ALDH1A1CYP2A6 | |
| SCHEMBL396846 | 0.65 | MMP3 (0.74) | LOXL2KIF11MMP3ALDH1A1CYP2A6 | |
| Water SCHEMBL11055485 | 0.65 | MMP3 (0.74) | LOXL2KIF11MMP3ALDH1A1CYP2A6 | |
| SCHEMBL22357718 | 0.64 | CYP2A6 (0.39) | KIF11MMP3ALDH1A1CYP2A6PTGS2 | |
| SCHEMBL20393470 | 0.64 | KIF11 (0.40) | LOXL2KIF11MMP3ALDH1A1CYP2A6 | |
| SCHEMBL360149 | 0.64 | LOXL2 (0.54) | LOXL2ALDH1A1CYP2A6GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502102-A1 | STING INHIBITORS | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2019-06-26 | — | — | EP | disclosed |