Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22598123 | 0.79 | RAB9A (0.38) | HTTALOX15PLK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20748738 | 0.71 | CYP1A2 (0.30) | POLB | |
| SCHEMBL4402960 | 0.71 | ALOX15 (0.63) | HTTALOX15PLK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6838562 | 0.70 | HTT (0.36) | HTTALDH1A1SMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL6838561 | 0.70 | HTT (0.36) | HTTALDH1A1SMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL21160404 | 0.69 | CTNNB1 (0.45) | TAS1R3TAS1R1 | |
| SCHEMBL22600767 | 0.69 | ATM (0.41) | LMNARAB9ANPC1CYP3A4MAPT | |
| SCHEMBL6879793 | 0.69 | HTT (0.49) | HTTALOX15PLK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6879786 | 0.69 | HTT (0.49) | HTTALOX15PLK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11062803 | 0.69 | ALDH1A1 (0.53) | HTTALOX15PLK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508223-B1 | COMPOSITION FOR ACTIVATING NEUROGENESIS | UNIV KYOTO (JP) | 2022-05-04 | — | — | EP | disclosed |
| EP-3508223-A1 | COMPOSITION FOR ACTIVATING NEUROGENESIS | Kyoto University (JP) | 2019-07-10 | — | — | EP | disclosed |