Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TGM2 | P21980 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393858 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDHCAR2TDP1 | |
| SCHEMBL5902084 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDHCAR2TDP1 | |
| SCHEMBL2393862 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDHCAR2TDP1 | |
| SCHEMBL17779954 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TGM2MAPTHPGDHCAR2 | |
| SCHEMBL4047404 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDHCAR2TDP1 | |
| SCHEMBL4047407 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDHCAR2TDP1 | |
| SCHEMBL21164212 | 0.77 | TGM2 (0.47) | ALDH1A1TGM2HCAR2TDP1MAPK1 | |
| SCHEMBL20412361 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDHCAR2TDP1 | |
| Perchlorate SCHEMBL10991932 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TGM2MAPTHPGDF13A1 | |
| Perchlorate SCHEMBL10991937 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TGM2MAPTHPGDF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350199-B2 | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof | SAMUMED, LLC (US) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10350199-B2 | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof | WNT1, WNT3, WNT3A | ALDH1A1 825/4885TGM2 3006/4885MAPT 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.