Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.44 |
| ▸ | RAF1 | P04049 | 4/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18181943 | 0.85 | HSD17B10 (0.47) | SMN1; SMN2RAB9AKDM4EALDH1A1ADORA2A | |
| SCHEMBL18177831 | 0.82 | LMNA (0.53) | SMN1; SMN2KDM4ERAF1ADORA1BRAF | |
| SCHEMBL4062589 | 0.76 | CACNA1G (0.44) | ADORA3ADORA2AADORA1MAPTADORA2B | |
| Hydrochloric Acid SCHEMBL4063245 | 0.75 | ADORA1 (0.52) | ADORA3ADORA2AADORA1ADORA2BTP53 | |
| SCHEMBL18177861 | 0.74 | MAPT (0.48) | SMN1; SMN2RAB9AALDH1A1MAPTNPC1 | |
| SCHEMBL13827682 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2RAB9AKDM4EALDH1A1ADORA1 | |
| SCHEMBL4502197 | 0.73 | AAK1 (0.64) | GSK3AGSK3B | |
| SCHEMBL31178157 | 0.72 | TP53 (0.71) | SMN1; SMN2TP53MAPK8GSK3B | |
| SCHEMBL16150892 | 0.71 | MEN1 (0.48) | SMN1; SMN2RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL29114911 | 0.71 | MAPT (0.65) | RAB9AADORA3ADORA2AADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071735-A1 | Compounds for Increasing Lipid Synthesis and Storage | WASE, NISHIKANT | 2020-03-05 | — | — | US | disclosed |
| US-10351883-B2 | Compounds for increasing lipid synthesis and storage | NUTECH VENTURES (US) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351883-B2 | Compounds for increasing lipid synthesis and storage | FASN, LIPC, SREBF2 | SMN1; SMN2 4517/4885RAB9A 3191/4885KDM4E 1755/4885 |
| US-20200071735-A1 | Compounds for Increasing Lipid Synthesis and Storage | FASN, LIPC, SREBF2 | SMN1; SMN2 4517/4885RAB9A 3191/4885KDM4E 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.