Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940936 | 0.96 | ALDH1A1 (0.64) | ALDH1A1NPC1POLBRAB9AMAPT | |
| SCHEMBL20500920 | 0.85 | AR (0.45) | ALDH1A1NPC1POLBRAB9AAR | |
| SCHEMBL20490864 | 0.85 | AR (0.45) | ALDH1A1NPC1POLBRAB9AAR | |
| SCHEMBL14941772 | 0.85 | ALDH1A1 (0.62) | ALDH1A1NPC1POLBRAB9AMAPT | |
| SCHEMBL6236056 | 0.79 | CHRM4 (0.49) | ALDH1A1POLBRAB9AMAPTTSHR | |
| SCHEMBL23636917 | 0.77 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9AMAPT | |
| SCHEMBL13651289 | 0.76 | AR (0.50) | MAPTARCHRM4 | |
| SCHEMBL14940383 | 0.76 | ALDH1A1 (0.97) | ALDH1A1NPC1POLBRAB9AMAPT | |
| SCHEMBL14941705 | 0.75 | TRIM24 (0.52) | ALDH1A1ARKDM4EKMT2AALDH1A3 | |
| SCHEMBL24988474 | 0.73 | AR (0.43) | ALDH1A1MAPTARKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210386734-A1 | DUAL MAGL AND FAAH INHIBITORS | LUNDBECK LA JOLLA RESEARCH CENTER, INC. | 2021-12-16 | — | — | US | disclosed |
| US-11129827-B2 | Dual MAGL and FAAH inhibitors | ABIDE THERAPEUTICS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20190282568-A1 | DUAL MAGL AND FAAH INHIBITORS | LUNDBECK LA JOLLA RESEARCH CENTER, INC. | 2019-09-19 | — | — | US | disclosed |
| US-10350205-B2 | Dual MAGL and FAAH inhibitors | ABIDE THERAPEUTICS, INC. (US) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129827-B2 | Dual MAGL and FAAH inhibitors | FAAH, FAAH2, MAG | ALDH1A1 1891/4885NPC1 1227/4885POLB 3776/4885 |
| US-20190282568-A1 | DUAL MAGL AND FAAH INHIBITORS | FAAH, FAAH2, MAG | ALDH1A1 1891/4885NPC1 1227/4885POLB 3776/4885 |
| US-10350205-B2 | Dual MAGL and FAAH inhibitors | FAAH, FAAH2, MAG | ALDH1A1 1891/4885NPC1 1227/4885POLB 3776/4885 |
| US-20210386734-A1 | DUAL MAGL AND FAAH INHIBITORS | FAAH, FAAH2, MAG | ALDH1A1 1891/4885NPC1 1227/4885POLB 3776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.