Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212049 | 0.96 | ABL1 (0.33) | ABL1MET | |
| SCHEMBL212746 | 0.94 | ABL1 (0.33) | ABL1MET | |
| SCHEMBL211133 | 0.94 | CTSK (0.35) | ABL1 | |
| SCHEMBL211083 | 0.94 | CTSK (0.35) | ABL1 | |
| SCHEMBL4342530 | 0.91 | ABL1 (0.35) | ABL1 | |
| SCHEMBL211680 | 0.91 | ABL1 (0.34) | ABL1MET | |
| SCHEMBL4343070 | 0.90 | ABL1 (0.34) | ABL1MET | |
| SCHEMBL211156 | 0.89 | CTSK (0.34) | ABL1MET | |
| SCHEMBL210583 | 0.89 | ABL1 (0.33) | ABL1 | |
| SCHEMBL209915 | 0.88 | PIN1 (0.34) | ABL1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | claimed |
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |