SCHEMBL21165037

SCHEMBL21165037

CCOC(=O)c1ccccc1Nc1ccc(C(c2ccc(Nc3c(C)cc(C)cc3C)cc2)c2ccc(Nc3c(C)cc(C)cc3C)cc2)c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 9/20 0.54
CDC25A P30304 1/20 0.51
CDC25C P30307 1/20 0.51
MAPT P10636 4/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
THRB P10828 2/20 0.43
METTL3 Q86U44 1/20 0.43
TP53 P04637 2/20 0.39
HPGD P15428 1/20 0.39
FTO Q9C0B1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21165365 0.96 CDC25B (0.50) CDC25BCDC25ACDC25CMAPTKDM4E
SCHEMBL21165313 0.89 CDC25B (0.58) CDC25BCDC25ACDC25CMAPTKDM4E
SCHEMBL21165196 0.88 CDC25B (0.60) CDC25BCDC25ACDC25CMAPTKDM4E
SCHEMBL21165036 0.82 RAPGEF4 (0.47)
SCHEMBL18351144 0.81 CDC25B (0.57) CDC25BCDC25ACDC25CMAPTKDM4E
SCHEMBL21165316 0.80 RAPGEF4 (0.43)
SCHEMBL21165052 0.78 RAPGEF4 (0.43) MAPTKDM4E
SCHEMBL21165197 0.78 RAPGEF4 (0.42) MAPTKDM4EHPGD
SCHEMBL21165308 0.75 THRB (0.35) CDC25BMAPTALDH1A1THRBTP53
SCHEMBL21165255 0.75 RAPGEF4 (0.46) FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 CDC25B 4620/4885CDC25A 4564/4885CDC25C 4678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.