SCHEMBL21165313

SCHEMBL21165313

CCOC(=O)c1ccccc1Nc1ccc(C(c2ccc(Nc3ccccc3C)cc2)c2ccc(Nc3ccccc3C)cc2)c2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 10/20 0.58
CDC25A P30304 1/20 0.55
CDC25C P30307 1/20 0.55
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 2/20 0.48
METTL3 Q86U44 1/20 0.43
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21165196 0.92 CDC25B (0.60) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL21165037 0.89 CDC25B (0.54) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL21165365 0.88 CDC25B (0.50) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL18351144 0.84 CDC25B (0.57) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL21165052 0.74 RAPGEF4 (0.43) KDM4EMAPTMEN1GAAKMT2A
SCHEMBL2008034 0.74 MAPT (0.71) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL10833818 0.73 CDC25B (0.65) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL18351202 0.72 CDC25B (1.00) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL3630708 0.72 KDM4E (0.67) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL21165374 0.71 HPGD (0.46) CDC25BCDC25AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 CDC25B 4620/4885CDC25A 4564/4885CDC25C 4678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.