Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21165163 | 0.83 | NFE2L2 (0.33) | NFE2L2ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL21165084 | 0.79 | ALDH1A1 (0.34) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL21164867 | 0.75 | ERN1 (0.50) | NFE2L2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL21165239 | 0.68 | — | — | |
| SCHEMBL17133355 | 0.67 | NPC1 (0.52) | ALDH1A1GAAMEN1KMT2ANPC1 | |
| SCHEMBL18198243 | 0.66 | NPC1 (0.54) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5790025 | 0.64 | NPC1 (0.52) | ALDH1A1GAANPC1RAB9AMAPT | |
| SCHEMBL4802700 | 0.63 | NPC1 (0.54) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1119892 | 0.62 | NPC1 (0.52) | NPC1RAB9APOLBMAPT | |
| SCHEMBL29404769 | 0.62 | NPC1 (0.52) | NPC1RAB9APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351706-B2 | Near-infrared fluorescent dyes and uses thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351706-B2 | Near-infrared fluorescent dyes and uses thereof | IK, CYBA, CRY2 | NFE2L2 1476/4885ALDH1A1 192/4885GAA 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.