Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.54 |
| ▸ | PGR | P06401 | 4/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.54 |
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284891 | 0.87 | NR3C1 (0.69) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL14450051 | 0.87 | NR3C1 (0.69) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL14285031 | 0.87 | NR3C1 (0.69) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL19887684 | 0.87 | NR3C1 (0.69) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL20553 | 0.87 | NR3C1 (0.69) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL20920716 | 0.83 | SMN1; SMN2 (0.53) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL20920720 | 0.81 | LMNA (0.60) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL18157023 | 0.81 | LMNA (0.60) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL18157024 | 0.81 | LMNA (0.60) | NR3C1PGRNR3C2ARLMNA | |
| SCHEMBL20920723 | 0.81 | NR3C1 (0.76) | NR3C1PGRNR3C2ARLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350223-B2 | Compositions and methods for treating ocular diseases | OCULAR RESOURCES LLC | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10350223-B2 | Compositions and methods for treating ocular diseases | NR3C2, MYLK, ALDH1A2 | NR3C1 11/4885PGR 1646/4885NR3C2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.