Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.69 |
| ▸ | PGR | P06401 | 4/20 | 0.69 |
| ▸ | AR | P10275 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.69 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14450051 | 1.00 | NR3C1 (0.69) | NR3C1PGRARLMNANR3C2 | |
| SCHEMBL14285031 | 1.00 | NR3C1 (0.69) | NR3C1PGRARLMNANR3C2 | |
| SCHEMBL19887684 | 1.00 | NR3C1 (0.69) | NR3C1PGRARLMNANR3C2 | |
| SCHEMBL14284891 | 1.00 | NR3C1 (0.69) | NR3C1PGRARLMNANR3C2 | |
| Dicirenone SCHEMBL120656 | 0.92 | NR3C1 (0.66) | NR3C1PGRARLMNANR3C2 | |
| SCHEMBL13988191 | 0.90 | NR3C1 (0.74) | NR3C1PGRARLMNANR3C2 | |
| SCHEMBL14284948 | 0.88 | NR3C1 (0.64) | NR3C1PGRARLMNANR3C2 | |
| SCHEMBL14450058 | 0.88 | NR3C1 (0.71) | NR3C1PGRARLMNANR3C2 | |
| SCHEMBL21165337 | 0.87 | NR3C1 (0.54) | NR3C1PGRARLMNANR3C2 | |
| SCHEMBL14567812 | 0.87 | NR3C1 (0.70) | NR3C1PGRARLMNANR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260027139-A1 | TREATMENT OF SLEEP APNEA WITH A COMBINATION OF A CARBONIC ANHYDRASE INHIBITOR AND AN ALDOSTERONE ANTAGONIST | VIVUS, INC. | 2026-01-29 | — | — | US | claimed |
| US-20250295634-A1 | USE OF ANTIANDROGENS TO TREAT SEPSIS | RHODE ISLAND HOSPITAL | 2025-09-25 | — | — | US | claimed |
| US-20240424053-A1 | METHODS AND COMPOSITIONS FOR PROVIDING MYOCARDIAL PROTECTION AND TREATING MYOCARDIAL STRESS AND FIBROSIS | TUFTS MEDICAL CENTER, INC. | 2024-12-26 | — | — | US | claimed |
| EP-3265103-B1 | COMPOSITIONS COMPRISING AN ALDOSTERONE ANTAGONIST FOR USE IN TREATING DRY EYES | YEE RICHARD W (US) | 2024-07-24 | — | — | EP | claimed |
| US-20240173337-A1 | METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA | APNIMED, INC. (DELAWARE) | 2024-05-30 | — | — | US | claimed |
| US-20240139224-A1 | TREATMENT OF SLEEP APNEA WITH A COMBINATION OF A CARBONIC ANHYDRASE INHIBITOR AND AN ALDOSTERONE ANTAGONIST | AMERICAN ENTERTAINMENT PROPERTIES CORP., AS LENDER | 2024-05-02 | — | — | US | claimed |
| EP-4313153-A1 | METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA | APNIMED, INC. (DELAWARE) (US) | 2024-02-07 | — | — | EP | claimed |
| WO-2023086390-A1 | METHODS AND COMPOSITIONS FOR PROVIDING MYOCARDIAL PROTECTION AND TREATING MYOCARDIAL STRESS AND FIBROSIS | TUFTS MEDICAL CENTER, INC. (US) | 2023-05-19 | — | — | WO | claimed |
| WO-2022204228-A1 | METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA | APNIMED, INC. (DELAWARE) (US) | 2022-09-29 | — | — | WO | claimed |
| US-20220175758-A1 | COMPOSITIONS AND METHODS TO TREAT NON-ALCOHOLIC FATTY LIVER DISEASES (NAFLD) | Coherus Biosciences, Inc. | 2022-06-09 | — | — | US | claimed |
| US-20020019522-A1 | Processes for preparation of 9-11, epoxy steroids and intermediates useful therein | NG JOHN S (US) | 2002-02-14 | — | — | US | claimed |
| US-20020016455-A1 | Processes for preparation of 9,11- epoxy steroids and intermediates useful therein | NG JOHN S (US) | 2002-02-07 | — | — | US | claimed |
| EP-1167381-A2 | Process for preparation of 7 alpha-carboxyl 9,11-epoxy steroids and Intermediates useful therein | G.D. Searle & Co. (US) | 2002-01-02 | — | — | EP | claimed |
| CN-1253564-A | Process for the preparation of 9, 11-epoxy steroids and intermediates useful therein | SEARLE & CO (US) | 2000-05-17 | — | — | CN | claimed |
| EP-0973791-A2 | PROCESS FOR PREPARATION OF 7 ALPHA-CARBOXYL 9, 11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN AND A GENERAL PROCESS FOR THE EPOXIDATION OF OLIFINIC DOUBLE BONDS | G.D. Searle & Co. (US) | 2000-01-26 | — | — | EP | claimed |
| EP-0944644-A2 | PROCESSES FOR PREPARATION OF 9,11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN | G.D. Searle & Co. (US) | 1999-09-29 | — | — | EP | claimed |
| CN-1209136-A | Process for the preparation of 7 alpha-carboxy 9, 11-epoxy steroids and intermediates used therein and general process for the epoxidation of olefinic double bonds | G D SEARRLE AND CO (US) | 1999-02-24 | — | — | CN | claimed |
| WO-1998025948-A9 | PROCESSES FOR PREPARATION OF 9,11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN | — | 1998-11-19 | — | — | WO | claimed |
| WO-1998025948-A2 | PROCESSES FOR PREPARATION OF 9,11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN | G.D. SEARLE & CO. (US) | 1998-06-18 | — | — | WO | claimed |
| WO-1997021720-A2 | PROCESSES FOR PREPARATION OF 7 ALPHA-CARBOXYL 9,11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN AND A GENERAL PROCESS FOR THE EPOXIDATION OF OLIFINIC DOUBLE BONDS | G.D. SEARLE AND CO. (US) | 1997-06-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260027139-A1 | TREATMENT OF SLEEP APNEA WITH A COMBINATION OF A CARBONIC ANHYDRASE INHIBITOR AND AN ALDOSTERONE ANTAGONIST | CYP21A2, HSD11B2, CA2 | NR3C1 187/4885PGR 3309/4885AR 383/4885 |
| US-20220175758-A1 | COMPOSITIONS AND METHODS TO TREAT NON-ALCOHOLIC FATTY LIVER DISEASES (NAFLD) | SLC10A1, LIPC, FABP1 | NR3C1 491/4885PGR 4156/4885AR 3137/4885 |
| US-20250295634-A1 | USE OF ANTIANDROGENS TO TREAT SEPSIS | SHBG, AR, HSD17B11 | NR3C1 53/4885PGR 1315/4885AR 2/4885 |
| US-20240139224-A1 | TREATMENT OF SLEEP APNEA WITH A COMBINATION OF A CARBONIC ANHYDRASE INHIBITOR AND AN ALDOSTERONE ANTAGONIST | CA4, CA9, CA7 | NR3C1 143/4885PGR 4018/4885AR 643/4885 |
| US-20020019522-A1 | Processes for preparation of 9-11, epoxy steroids and intermediates useful therein | CYP4A11, HSD11B1, DHCR7 | NR3C1 32/4885PGR 1062/4885AR 205/4885 |
| US-20020016455-A1 | Processes for preparation of 9,11- epoxy steroids and intermediates useful therein | CYP4A11, HSD11B1, DHCR7 | NR3C1 36/4885PGR 1034/4885AR 210/4885 |
| US-20240424053-A1 | METHODS AND COMPOSITIONS FOR PROVIDING MYOCARDIAL PROTECTION AND TREATING MYOCARDIAL STRESS AND FIBROSIS | TNNT2, TNNI3, MMP1 | NR3C1 796/4885PGR 2077/4885AR 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.